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Recent preclinical mouse models have shown that immune-targeting the xCT antigen can enhance the activity of a viral vectors-based vaccine against HER2, and reduces the growth of HER2+ breast cancer, frequency of CSCs and metastatic events (85)

Moreover, p53 inactivated with enhanced ubiquitination was found to be associated with the invasion or recurrence of endometrial cancer ( via activation of the HippoYAP pathway (Wen et al., 2020)

5c), introduced a photocaged variant (opto-dNCL#T1) for spatiotemporally controlled degradation upon UV irradiation [236]

Int J Dermatol 58(6):649658

Autoantibodies of the IgG class are generated in patients with GD that bind to IGF-IR and initiate the signaling from the TSHR/IGF-IR physical and functional protein complex